LEVOTHYROXINE: Patient Information Sheet - Instructions before taking Levothyroxine.

Patient Information Sheet - LEVOTHYROXINE.

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Brand names in Kenya - Euthyrox, Thyrion, Telithro, Thyrox, Tyroberg.

Levothyroxine is a medication commonly prescribed for patients with hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. This guide will help you understand how to take levothyroxine properly to ensure you get the most benefit from your treatment, as well as answer the following questions that we get asked a lot by our patients:

1. How long will it take for levothyroxine to start working?

2. What time of day should I take my levothyroxine dose?

3. Are there any foods or medications I should avoid while on levothyroxine?

4. What side effects should I watch for while taking levothyroxine?

5. Will I need to take levothyroxine for the rest of my life?

Instructions Before Taking Levothyroxine

1. Take on an empty stomach: Levothyroxine should be taken at least 30-60 minutes before breakfast or any meal. This ensures maximum absorption of the medication.

2. Take with water: Swallow the tablet with a full glass of water. Avoid taking it with coffee, milk, or other drinks as these can affect absorption.

3. Consistency matters: It is important to take your levothyroxine at the same time every day for the best results.

4. Avoid taking with other medications: Wait at least 4 hours before taking other medications, particularly those that may interfere with levothyroxine absorption (see table below).

5. Routine blood tests: Your doctor will check your thyroid hormone levels regularly to ensure your dose is correct. Always follow your healthcare provider's advice on when to have these tests.

6. Report any side effects: If you experience symptoms like palpitations, weight changes, or mood swings, inform your doctor. These may be signs of an inappropriate dose.

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Factors	Effect on Levothyroxine levels	Examples
Medications that decrease the absorption of Levothyroxine	Decrease levels	Iron Supplements, Calcium Supplements, Antacids (Containing aluminium or magnesium e.g. Gaviscon, Relcer gel, ), Sucralfate, Cholestyramine
Medications that increase clearance of Levothyroxine	Decrease levels	Phenytoin, Carbamazepine, Phenobarbital (Convulsions medications) and Rifampin (Tuberculosis medication)
Medications that decrease the metabolism of Levothyroxine	Increase levels	Estrogen, Oral Contraceptive pills, Tamoxifen, Raloxifen.
Gastrointestinal conditions	Decrease Absorption	Celiac Disease, Crohn's Disease, Lactose Intolerance
Liver / Kidney disease	Alter drug metabolism	Chronic kidney and Liver disease (cirrhosis).
Pregnancy	Increase demand for levothyroxine	Pregnant women may need higher doses due to increased thyroid hormone requirements.
Food interactions	Decrease absorption	Higher fibre foods, Soy products, Coffee

Important Reminders on taking levothyroxine

• Missed Dose: If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed dose and take your regular dose. Do not double up.

• Interactions: Always inform your doctor or pharmacist about all the medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.

• Pregnancy and breastfeeding: If you are pregnant or planning to become pregnant, let your doctor know. Levothyroxine is generally safe during pregnancy, but dose adjustments may be necessary.

  
  

Managing Hypothyroidism in Kenya

If you're in Nairobi or elsewhere in Kenya and living with hypothyroidism, access to reliable treatment and regular medical care is essential. Many pharmacies and clinics provide levothyroxine, and the medication should be taken under the supervision of a healthcare provider. Maintaining open communication with your doctor and attending regular follow-ups will help ensure that your thyroid levels remain stable and that you live a healthy, balanced life.

For more information on thyroid disease and hypothyroidism in Kenya, visit us at Doctors Park - 3rd Parklands Avenue.

Thyroid disorders - Care & Management

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Conclusion

Proper use of levothyroxine is essential for managing hypothyroidism effectively. Following these instructions can help optimize your treatment and improve your quality of life. Always consult your healthcare provider if you have questions or concerns about your medication or condition.

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